1/5

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21c Museum Hotel St Louis

St. Louis • Downtown • SPLURGE

avg. $407 / night

Includes $21 / night in cash back

Cash back is redeemable via Virtual Visa, Venmo, or bank transfer starting 24-48 hours after check-out

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Cash back

5% cash back on all completed stays (redeemable via Virtual Visa, Venmo, or bank transfer starting 24-48 hours after check-out)

Credit card points

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Hotel loyalty points

Points accrual and status eligibility with major hotel loyalty programs: Marriott Bonvoy, Hilton Honors, World of Hyatt, and others

Free breakfast

Breakfast-included rate options available

Room upgrades

Complimentary room upgrades (subject to property availability)

Extend your stay

Early check-in and late check-out (subject to property availability)

Location

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At a glance

A 1924 YMCA conversion with preserved original pool, Deborah Berke interiors, and integrated contemporary art programming.

Best for: Art collectors and architecture enthusiasts

Highlights:

  • 1924 Romanesque Revival YMCA with original pool and mosaic tilework
  • Interiors by Deborah Berke Partners with contemporary art throughout
  • Double-height bar with curved wooden reveals and figurative paintings
Civic-modernart-forward

PB hotel design editorial

Erected in 1924 as the St. Louis YMCA, the twelve-storey Romanesque Revival tower on Locust Street carries its origins with unusual candor — the words Swim For Life still set into the pool floor in mosaic tile, the original amber and ochre tilework lining walls that predate the city's mid-century exodus by decades. 21c Museum Hotel St. Louis, which took over the building in 2017, made the right call in leaving that pool exactly as found: it remains one of the more quietly moving rooms in American hospitality, a preserved social institution repurposed without sentimentality. The conversion, designed with interiors by Deborah Berke Partners — the architecture practice behind the entire 21c chain — layers contemporary art programming over the building's civic bones with a calibrated irreverence. Guestrooms pair channeled upholstered headboards and herringbone-patterned carpets in warm taupe with mid-century-inflected brass-and-black pendant fixtures and bright accent chairs in burnt orange, while larger suites introduce moss-green velvet sectionals and sculptural art objects — a oversized red penguin, the brand's recurring mascot, stationed with deadpan confidence beside the bed. The bar and restaurant space is the boldest gesture: double-height arched windows fitted with dramatically curved wooden reveals frame a marble-topped oval bar clad in deep burgundy tile, large-scale figurative paintings covering the remaining wall plane. The exterior's limestone base and corbelled brick cornice, dramatically illuminated at dusk, make clear that the building was always worth saving.

Travel notes

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About

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Amenities

Pool

Internet

Suites

Room service

Free Internet

Wheelchair Access

Restaurant

Bar/Lounge

Pets Allowed

Wifi

21c Museum Hotel St Louis Reviews

195 reviews

"Stayed here due to a graduation. It was an edict property from Chase travel. Overall the property was nice but except for the museum on the second floor, it has a tired look that needs to be refreshed. Or at least a coat of paint for the hallway on the third floor. Bathroom was dark and spacious but didn't have any makeup accessories like a q-tip. The hotel's restaurant leans to Spanish food. With few restaurants nearby it was crowded. There is no free parking nearby. Parking lots and garages. 21C charges $50 per 24 hours. What was extremely annoying is that you cannot use the Edict hotel credit towards parking. Finally, there is breakfast and lunch at the Good Press. There was always a line for something for breakfast. That is not a hardship, but waiting 34 minutes to receive French Toast is."

A Tripadvisor traveler review

May 18, 2026

"Very well designed rooms and super interesting lobby. Definitely a fun and unexpected location. However the high-end products in the hotel room in the bathroom are always empty and the dispensers do not work, which requires multiple calls to get anything resolved. Restaurants are excellent but there’s a very long wait for breakfast since everyone has a credit. And do not expect to walk anywhere because there is nothing worth seeing within walking distance so everything will be an Uber from here."

A Tripadvisor traveler review

May 17, 2026

"I had business in St Louis so stayed here for a few nights. St Louis could sure use the business as the city has lots of vacant buildings and signs of entrenched poverty. The room was small for the American Midwest, but perfectly fine for 1-2 people. The location is odd. The eerily quiet neighborhood doesn't have much to offer a business traveler. If you're going in/out of the airport, this location is about a .6 mile walk from Union Station, which has a great train to the airport, but .6 miles is far if you have suitcases. If you want to go for a run along riverside, that's about .7 miles from this hotel (kind of far if want to go for a quick run). There are a few restaurants nearby but many of them close at 7 PM or earlier, and don't open at all Monday-Tuesday. The in-hotel restaurant is insanely priced at $50+ for an entree, and I didn't eat there. The hallways have peeling wallpaper and worn carpet, but the condition of my hotel room was better. The very nice in-house fitness center was a reason to pick the hotel, but the AC was broken when I was there and the fitness room was a toasty 78 degrees F, making for a poor experience. The outsourced cleaning staff is clearly overwhelmed; my room wasn't cleaned by 5 PM when I returned from work so I opted out of room cleaning. The lobby is beautiful and art gallery a nice touch, but this hotel doesn't get the basics right."

A Tripadvisor traveler review

May 13, 2026

"Amazing experience! Atmosphere, amenities and service was exceptional."

A Tripadvisor traveler review

Apr 26, 2026

"Hallways and room felt dirty. Bathroom appears to not be cleaned. Refrigerator was in room but unplugged, phones in room not working and had to call front desk from mobile to have them bring a tv remote to room because there wasn’t one in the room. Most disappointing was valet wrecked my truck, apologized and accepted responsibility on the sidewalk as they pulled my truck up, they filed a claim through PMC their “Parking Management Company” and PMC denied the claim stating “ Our management team conducted a thorough inspection of the property, including the driving path and the vehicle parking area, and we were unable to identify any factors that could have contributed to the damage. There was no damage to any other vehicles or fixed objects that could account for the reported damage.” Would strongly encourage you to stay somewhere else."

A Tripadvisor traveler review

Apr 17, 2026

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